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diagnosis differential management hematology dermatology neurology classification lupus ophthalmology signs sle symptoms disease purpura rash thrombocytopenia treatment algorithm ana anca
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
central nervous system ... Churg-Strauss syndrome ... disease - systemic ... lupus erythematosus ... Vessels #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... ANCA associated vasculitis ... Arthritis (RA), Systemic ... lupus erythematosus ... Differential #Diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ischemia - Skin: erythematous ... • Cogan Syndrome ... lupus erythematosus ... differential #diagnosis #rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
central nervous system ... Inflammatory causes ... • Systemic lupus ... erythematosus ... ANCA-associated vasculitides
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... drug-induced SLE) • Systemic ... • Sjögren syndrome ... antibodies #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... #erythematosus ... symptoms #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... lupus erythematosus ... classification #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , macular, patchy ... ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... #Diagnosis #Rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... Purpuric Dermatosis: Schamberg ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #rheumatology #
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... #differential #hematology
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