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diagnosis lupus syndrome classification differential disease erythematosus treatment vasculitis behcet behcets cerebritis cns comparison dermatology druginduced hcq hodgkins hydroxychloroquine levels
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Positive in 60-80% of cases ... #lupus #Systemic ... #Summary #rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels ... #lupus #management
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
refractory lesions Ocular ... Neuro disease: • Systemic ... Syndrome #Treatment #management ... #pharmacology # ... rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... months to years) Systemic ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... • Arthritis: SLE ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ulcers, cutaneous, ocular ... Syndrome: - Ocular ... vasculitis, and SLE ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... tract, and often causes ... ulcers, cutaneous, ocular ... Cogan syndrome: Ocular ... Differential #Diagnosis #Rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
involvement: May involve anterior ... Rule out other causes ... sites such as the collar ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
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