28 results
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Approach to suspected Heparin-Induced ... Algorithm • "4 T's" clinical ... NephPrasad #Heparin ... Thrombocytopenia #HIT #hematology ... #diagnosis #4Ts
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... Diagnosis and Management ... hemoglobin/hemosiderin, Hepatic ... #Diagnosis #Management ... #Algorithm #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... Hepatic, Portal, ... #Diagnosis #Algorithm ... #Causes #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
approach to the diagnosis ... based primarily on clinical ... Estimates of the clinical ... #Hematology #HIT ... #Heparin #Induced
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... thrombin inhibitors, heparin ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Thrombocytopenia (HIT) - Diagnosis ... thrombocytopenia Diagnosis ... : • Clinical Suspicion ... A/C if clinical ... Management #Treatment #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
studies suggest net clinical ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology ... #Diagnosis
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • ... splenomegaly • Hepatic ... management #treatment #rheumatology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
unfractionated heparin ... cause e.g. heparin ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... dysfunction (25%) • Hepatic ... 100mg/dL) - Heparin ... #Coagulation #diagnosis ... treatment #management #hematology