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differential rheumatology management nephrology sle dermatology hematology pulmonary table types vasculitis acute aki allergy alopecia comparison druginduced erythematosus hairloss hypersensitivity
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Post/pauci immune glomerulonephritis ... S - Systemic Lupus ... Hypocomplementemia #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... - Differential Diagnosis ... Algorithm Red ... • Lupus glomerulonephritis ... #Algorithm #Causes
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... - Differential Diagnosis ... Algorithm Reactive ... • Systemic Lupus ... #Algorithm #Causes
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... - Differential Diagnosis ... Algorithm Acute ... Rapidly Progressive Glomerulonephritis ... #Algorithm #Causes
Lupus Nephritis Primer Class I - Minimal Mesangial Class II - Mesangial Proliferative Class Ill - Focal Proliferative Class IV
Lupus Nephritis ... Proliferative Class IV - Diffuse ... Nephritis #SLE #Classification ... #Classes #differential ... #diagnosis #management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... Discontinuation of causal ... • Immunologic Workup ... #rheumatology #diagnosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement ... Erythematosus #Diagnosis
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
Bronchiectasis: diagnosis ... management Causes ... of localized -> diffuse ... #Differential #workup ... #algorithm #pulmonary
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Causes of Hemoptysis ... Algorithm Massive ... • Bronchitis Diffuse ... Vasculitis • Lupus ... #Algorithm #Causes
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