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diagnosis differential nephrology causes algorithm management clinical pocus ultrasound pharmacology pathophysiology kidney rheumatology table treatment hematology classification signs workup symptoms
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Membranoproliferative Glomerulonephritis ... staining (lg + complement ... MGPN • Complement ... Membranoproliferative #Glomerulonephritis ... nephrology #diagnosis #renal
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Membranoproliferative glomerulonephritis ... Post/pauci immune glomerulonephritis ... Erythematosus (total 50, renal ... Hypocomplementemia #Low #Complement
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... rapidly progressive glomerulonephritis ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... Levels: Scleroderma Renal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... - Necrotizing glomerulonephritis ... , pauci-immune glomerulonephritis ... against MPO • Complement ... • Urinalysis (Renal
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive Glomerulonephritis ... staining): • Low Complement ... Idiopathic • Normal Complement ... Kidney: Anti-GBM Glomerulonephritis ... #Progressive #Glomerulonephritis
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
) - Prerenal, Renal ... Postrenal PRE-RENAL ... Vascular occlusion RENAL ... Glomerulonephritis ... Infection POST-RENAL
Complement Pathways - Classical Pathway - Lectin Pathway - Alternative Pathway #Complement #Pathway #hematology #pathophysiology
Complement Pathways ... Alternative Pathway #Complement
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome: - Acute poststreptococcal glomerulonephritis - Rapidly progressive
poststreptococcal glomerulonephritis ... Rapidly progressive glomerulonephritis ... proliferative glomerulonephritis ... Membranoproliferative glomerulonephritis
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
protein/Cr - Renal ... - 45% - Pre-renal ... mostly ATN and pre-renal ... related) - Glomerulonephritis
Spectrum of Glomerulonephritis Pathology - Common Diseases - Typical Presentation By Dr. John Roberts @John_K_Roberts #Glomerulonephritis #Spectrum
Spectrum of Glomerulonephritis ... John_K_Roberts #Glomerulonephritis
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