898 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 • SLE ... • Infection eg SBE ... ThePeanutKidney #Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... Diagnosis and Management ... 80% - Low complement ... Usual therapeutic management ... Erythematosus #Diagnosis #Management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... 80% - Low complement ... Usual therapeutic management ... rheumatology #diagnosis #management
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Erythematosus #SLE
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
General Algorithms for Assessment of the Left Ventricular Assist Device (LVAD) (Algorithms 1, 2 and 3)

Algorithm
General Algorithms ... Device (LVAD) (Algorithms ... 1, 2 and 3) Algorithm ... LVAD) Patient Algorithm ... #Management #BMJ
Bronchiectasis: diagnosis and management 

Causes of localized -> diffuse bronchiectasis
Foreign body, Bronchial stenosis (tumor, .. ),
diagnosis and management ... RA, Sjögren, SLE ... Bronchiectasis #diagnosis #management ... Differential #workup #algorithm
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... tagged with C3 complement ... - Activate Complement ... classical pathway (see ... Complement Activation
Suggested Treatment Algorithms for the Management of Polymyalgia Rheumatica and Giant Cell Arteritis

#Management #Algorithm #GCA #PMR
Suggested Treatment Algorithms ... for the Management ... Cell Arteritis #Management ... #Algorithm #GCA