433 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 • SLE ... • Infection eg SBE ... ThePeanutKidney #Complement
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement ... Kumfer @AnnKumfer #Pulmonary
Pulmonary Embolism on POCUS Echocardiogram

Mid 30's female with chest pain/dyspnea.  Triage EKG (no prior).
Pulmonary Embolism ... on POCUS Echocardiogram ... See thread for POCUS ... Pulmonary embolism ... RJonesSonoEM #Pulmonary
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Erythematosus #SLE
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement ... management of SLE ... Lupusreference #SLE
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary
Atypical HUS - Hemolytic Uremic Syndrome
Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
autoimmune like SLE ... It is complement ... renal, cardiac, pulmonary ... with Eculizumab (complement
POCUS Findings in Acute Pulmonary Embolism
- McConnell's Sign
- TAPSE
- D-Shaped Septum
- Abnormal RV:LV Ratio

#Pulmonary #Embolism #AcutePE
POCUS Findings in ... Acute Pulmonary ... RV:LV Ratio #Pulmonary ... AcutePE #Accuracy #POCUS
Pulmonary Hypertension - Classification, Evaluation, POCUS Assessment

#PHTN #Pulmonary #Hypertension #Classification #Evaluation #POCUS #Assessment #Groups
Pulmonary Hypertension ... Classification, Evaluation, POCUS ... Assessment #PHTN #Pulmonary ... Classification #Evaluation #POCUS