11 results
diagnosis nephrology differential glomerulonephritis rheumatology workup nephrotic renal acute aki blood clinicopathology cryoglobulinemia cryoglobulins disease gammopathy hematuria initial injury kidney
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... staining (lg + complement ... MGPN • Complement ... immune deposits on EM
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... present on repeat testing ... including overnight testing ... • Drugs Glomerular ... #Causes
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... #testing #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... - Skin, glomeruli ... : - Kidneys: glomerular ... against MPO • Complement ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... - Small vessel vasculitis ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... Kidney #Injury #Classification
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... mimics, repeat testing ... • Evidence of glomerular ... Nephrology if cause ... Hematuria #Diagnosis #Algorithm
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... diagnosis #initial #testing
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... • Vasculitis ... diagnosis #types #classification
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... should use this algorithm ... smallpox-diagnostic-algorithm-poster ... variola virus* PCR testing ... initiation of any testing
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