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diagnosis rheumatology differential dermatology sle classification cryoglobulinemia erythematosus neurology syndrome systemic treatment cerebritis cns comparison cryofibrinogenemia cryoglobulinemic cryoglobulins druginduced erythema
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... immunofluorescence Immune Complex ... Post-strep GN, Lupus ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tracts Immune Complex ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... differential #diagnosis #rheumatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
- Diagnosis, causes ... and management ... Clinical manifestations ... with refractory disease ... #Rheumatology #
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... (lupus, RA, Sjogren's ... Work Up: • Complete ... #Causes #dermatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... Evolution: Chronic disease ... #Summary #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Syndrome: • Clinical ... • Autoimmune diseases ... (e.g. systemic lupus
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Cryofibrinogenemia Clinical ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... Evolution: Chronic disease ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Diagnosis and Management ... Caused by intrapulmonary ... shunt (Type 2) Clinical ... HPS features - Complete ... #treatment #hepatology
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