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diagnosis clinical differential echocardiogram ultrasound rheumatology management radiology signs symptoms cardiac classification effusion ekg electrocardiogram orthopedics pericardial pericarditis s4c a4c
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Manifestations • Immune Complex ... Myopathy (Also caused ... #MSK #Musculoskeletal ... Complications #pathophysiology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... inflammation (complex ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitis and Vasculitides ... tracts Immune Complex ... Vasculitis • ... tract, and often causes ... , and SLE) • Urinalysis
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... self-antigens are the cause ... Erythematosus (SLE ... antigens are the cause ... Allergy #Immunology #pathophysiology
Causes of Diffuse Lung Disease. Collagen vascular - Scleroderma - Rheumatoid arthritis -
Causes of Diffuse ... Dermatomyositis - SLE ... - Toxic gas Vasculitides ... #Diagnosis #Radiology ... #Differential #Causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... immunofluorescence Immune Complex ... Glomerulonephritis #Vasculitis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
deposit of immune complexes ... • They can cause ... Cryoglobulins Cause ... diseases: - 10% SLE ... erythematosus (SLE
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... Rheumatologic: SLE ... Mediterranean Fever • Vasculitis ... Differential #Diagnosis #Causes ... #cardiology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... adhesion of IgA complexes ... Formation of immune complexes ... periumbilical region), nausea ... HenochScholeinPurpura #Pathophysiology
Ruptured Chordae Tendineae on POCUS Echocardiogram Many underlying causes, not limited to: MVP, subacute endocarditis, connective
Chordae Tendineae on POCUS ... Many underlying causes ... for MR when you see ... Chordae #Tendineae #POCUS ... Ultrasound #Clinical #Cardiology
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