40 results
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Manifestations • Immune Complex ... Myopathy (Also caused ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... / Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... chromosome 21) Signs / Symptoms ... / Complications ... AlzheimersDisease #Dementia #pathophysiology ... diagnosis #signs #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... #Retinopathy #pathophysiology ... #ophthalmology ... diagnosis #signs #symptoms ... #complications
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... / Complications ... Syndrome #MSK #pathophysiology ... #diagnosis #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation (complex ... Manifestations #pathophysiology ... diagnosis #signs #symptoms ... #complications
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
retinal ischemia causes ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• Significant cause ... most frequent cause ... / Complications ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Mechanical Bowel Obstruction and Ileus - Pathogenesis and Clinical Findings
Ileus: Functional bowel "blockage", no peristalsis
Mechanical Obstruction:
of bowel lumen Complete ... pain and related symptoms ... bowel-movements (suggests complete ... percussion • Nausea ... obstruction #sbo #ileus #pathophysiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
extrapulmonary cases ... Clinical Signs/Symptoms ... back pain - Symptoms ... decreased reflexes Pathophysiology ... Mycobacterium tuberculosis complex