40 results
Two-step Copeptin algorithm for differential diagnosis of Diabetes Insipidus (DI)

Baseline Copeptin < 21.4 pmol/L:
 • Arginine-stimulated
Two-step Copeptin ... Diabetes Insipidus (DI ... partial Central DI ... → Nephrogenic DI ... Diabetes #Insipidus #DI
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Management #Algorithm #Sodium ... nephrology #insipidus #DI
Hypernatremia - Diagnostic Evaluation Algorithm
Step 1: Consider history. Most patients presenting with hypernatremia are either very
If patient has DI ... Evaluation #Algorithm #Sodium
Brugada syndrome with non-sustained VT; sodium channel blocking drugs (e.g. amio, procainamide) can be dangerous here!

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Brugada syndrome ... non-sustained VT; sodium ... amalmattu #Brugada #syndrome
Hypernatremia Classification and Features According to Volume Status
 - Hypervolemic hypernatremia - Cushing's syndrome, Primary hyperaldosteronism,
hypernatremia - Cushing's syndrome ... hypernatremia - DI ... Central Dl, Partial DI ... , Gestational DI ... , Nephrogenic DI
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
transporter Bartter syndrome ... limb Gitelman syndrome ... tubule Liddle syndrome ... cell epithelial sodium ... of epithelial sodium
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Increased renal sodium ... • Nephrotic Syndrome ... • Nephrotic syndrome ... Respiratory Distress Syndrome
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... hypertrophy • Sodium ... #cardiorenal #syndrome
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... dr_missyhanna #Gitelman #Syndrome
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Cirrhosis, Nephrotic syndrome ... Algorithm #diagnosis #sodium