8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Prednisone 5mg/kg ... Imaging: CXR- pulmonary ... #management #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... erythematosus (ACLE ... Differential Diagnosis ... . hematologic) ... Clinical Features
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... / hypoxemia -> focus ... output - Acute pulmonary ... - Compartment syndrome ... lactate and can act
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... • In all patients ... or triggers) is crucial ... Clinical Presentation ... #Management #Hematology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... filling +++ (risk of pulmonary ... ) • IVIg 2 g/kg ... #diagnosis #management ... timeline #treatment #rheumatology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... relatives (if all ... Marfan syndrome, ... peds #pediatrics #diagnosis ... #hematology #primarycare
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Diagnosis (Clinical ... evaluation essential in all ... #Hepatorenal #Syndrome ... #Hepatology #Nephrology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... median age at diagnosis ... cardiovascular or pulmonary ... importance of clinical ... #algorithm #hematology