43 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... ), PAH (pulmonary ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... prevention (statin for CVA ... #rheumatology # ... #management #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... • Immunologic Workup ... Evolution: Chronic disease ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... solid cancers • Systemic ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... suspicion of severe disease ... guidelines General - Systemic ... Rheumatology ... Peds #Pediatrics #Diagnosis
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
rainwater catchment systems ... non-productive cough, nausea ... failure • Severe pulmonary ... disease ARDS Diagnosis ... #treatment #management
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Causes of acute ... Systemic disease ... Chronic #Diarrhea #management ... #algorithm #workup ... #diagnosis #differential
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... months to years) Systemic ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... mononeuritis multiplex WORKUP ... Goodpasture's cause ... #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... progressing GN • New pulmonary ... tract, and often causes ... Differential Diagnosis ... #rheumatology #