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differential hepatology management liver algorithm rheumatology causes transaminitis arthritis pain classification clinical disease joint nephrology oncology ophthalmology physicalexam syndrome workup
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... Hepatopathy • Acute ... Viral Hepatitis ... Drug-induced liver injury ... #hepatology #transaminitis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... Patterns #Liver #Injury ... #hepatology #LFTs ... #differential #diagnosis
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe Acute ... Liver Injury ... Drug-Induced liver injury ... #Differential #Hepatology ... #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... • Infections: Hepatitis ... #hepatology #algorithm ... Transaminitis #LFTs ... #hepatitis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Sophia_Hayes_MD #Liver #Injury ... #Differential #Diagnosis ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... viral hepatitis ... liver #chemistry #diagnosis ... #differential #Hepatology ... transaminitis #LFTs
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Cell Disease Acute ... Supportive with treatment ... Hepatobiliary #hepatology ... #hepatitis #differential ... #diagnosis
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... immunosuppression • Acute ... with severe liver injury ... > 3 mg/dL) or acute ... liver failure #HepatitisB
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