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hematology management neurology algorithm oncology abnormal apml arterial barre cardiology cardiomyopathy causes comatose differentiation embolism encephalopathy enzymes gbs guillain leukostasis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Restrictive Cardiomyopathy - Diagnosis and Causes Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema) Physical
↑ "Right Sided-Symptoms ... Echocardiography, Cardiac MRI ... : Amyloidosis (AL ... Hyper-eosinophilc Syndrome ... #Causes #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... • Nephrotic Syndrome ... considered in all ... Venous #Arterial #pathophysiology ... #hematology #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Vascular narrowing on MRA ... circulation: MCA ACA ... Reversible course Differential
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... - Spinal MRI may ... Guillain #Barre #Syndrome
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... box indicates all ... presence of metabolic syndrome ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... transformation to AML ... blood count with differential ... progression to AML ... #diagnosis #hematology
The Neurological Evaluation of a Comatose Patient Definition: • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... Diagnosis: • ... • Locked-in syndrome ... • Mutism Pathophysiology ... caseyalbin #PhysicalExam
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