10 results
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
(IRIS): • In HIV ... Worsening of previous neurologic ... lymphadenopathy, pulmonary ... Children with pulmonary ... differential #TB #neurology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... TB: • HIV • Recent ... • HIV: 2/3 pulmonary ... TST or IGRA HIV ... : • HIV-infected
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(LTBI) Pathophysiology ... TB: • HIV • Recent ... • HIV: 2/3 pulmonary ... TST or IGRA HIV ... : • HIV-infected
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in Tuberculosis ... Clinical Signs/Symptoms ... of active pulmonary ... decreased reflexes Pathophysiology ... for concomitant pulmonary
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
status, and focal neurologic ... 80% sensitive Tuberculous ... - Hemorrhage, tuberculomas ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... • Steroids: IV ... Differentiation #Syndrome #APML
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
dementia Pathophysiology ... • Depressive symptoms ... is similar to PML ... etiologies and PML ... dementia #AIDS #Neurology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
• Congenital hip ... Chondrodysplasia Neurologic ... Poliomyelitis Activity ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Lymphadenitis, pulmonary ... lymphadenitis, pulmonary ... , hypoxia, and pulmonary ... leukoencephalopathy (PML ... • Persistently active
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... fasciculations Common Symptoms ... motor neurons - IV ... Lateral #Sclerosis #neurology