21 results
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... symptoms - Pel-Ebstein ... involvement Differential ... Malignancies (eg CML, ALL ... #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Lymphoma Treatment ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Hemopathies+++: Hodgkin ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... • Bicytopenia Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    • Dexamethasone
trigger • Almost all ... or autoimmune disease ... for refractory disease ... #Treatment #management ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... Fever is the main clinical ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
The hematopoietic tree and the resulting leukemias and lymphomas 
The hematopoietic tree refers to the hierarchical
self-renew and differentiate ... into all types ... cells, which are crucial ... on the rate of disease ... non-Hodgkin lymphoma
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
identical to the non-Hodgkin ... Orange or Hep C Clinical ... cells can indicate disease ... microglobulin Treatment ... leukemia, Hodgkin
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Diagnosis and Management ... Lung Abscess - Clinical ... Clindamycin in case of PCN ... Lung Abscess Differential ... Abscess #pulmonary #differential