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diagnosis anemia hematology differential workup aiha disease nephrology nephrotic agglutinin antiglobulin causes direct glomerulonephritis hemolysis initial nephritic nephritis pathophysiology table
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... DAT Negative Hemolysis ... , C3d ( +/- ) Cold ... ) Paroxysmal cold ... #Autoimmune #Hemolysis
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... blood smear + DAT ... Heinz bodies, DAT ... idiopathic, malignancy, autoimmune ... Differential #Diagnosis #Algorithm
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA Warm AIHA: - 70%; IgG mediated -
Autoimmune Hemolytic ... IgG mediated - DAT ... Smear: spherocytes Cold ... IgM mediated - DAT ... #Hemolytic #Anemia
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... AIHA (48-70%) Cold ... Mixed-type AIHA (7-8%) DAT-negative ... MatthewHoMD #Autoimmune ... #Hemolytic #Anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... Positive Coombs testing ... post infectious setting ... CLL (older) • Autoimmune ... blood cells (RBCs) at
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Agglutination - Cold ... elliptocytosis, autoimmune ... Differential #Diagnosis #Algorithm ... workup #hematology #testing
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... exceeds 500 mg/day ... LDH - Assess for hemolysis ... ), and certain autoimmune ... #testing #workup
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... exceeds 500 mg/day ... LDH - Assess for hemolysis ... ANA - Screen for autoimmune ... ), and certain autoimmune
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