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diagnosis management table algorithm cardiology comparison differential druginduced erythematosus hematology infectiousdiseases summary systemic acidosis aspergillus cancer cardiomyopathy cerebritis chest chf
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... • Evolution: ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation ... #summary #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... symptoms • Rheumatologic ... to 12 weeks for acute ... has five major clinical ... stain of clinical
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... HIV/AIDS, CGD) Clinical ... presentations: • Pulmonary ... septated hyphae, acute ... #fungal #infectiousdiseases
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... without other cause ... : 33% • Treatment ... At least 3 of (Acute ... , and CXR with pulmonary
Empyema Necessitans (EN) on Chest Wall Physical Examination Pulmonary teaching case: you are called to the bedside
Examination Pulmonary ... This is what you see ... most common) - Fungus ... Fusobacterium Treatment ... #PhysicalExam #clinical
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 Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
again we might see ... before beginning treatment ... cardiac output - Acute ... pulmonary edema ... peritonitis - Acute
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
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