10 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
B-LNH), solid cancers ... Treatment: • ... inhibitors under evaluation ... diagnosis #management #treatment ... #summary #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... - Acute Bleeding ... by a hemophilia treatment ... center. ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... At least 3 of (Acute ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... antithrombin, protein ... Treat primary cause ... #treatment #management ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
first step in evaluation ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... inflammation (acute ... differential #diagnosis #hematology
Pulmonary Nodule
Evaluation is guided by nodule size & assessment of probability of malignancy. In addition is
Evaluation is guided ... are called lung masses ... malignant until proven ... The treatment of ... diagnosis of lung cancer
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... with no urine protein ... filling +++ (risk of pulmonary ... spacing of IVIg cures ... #rheumatology
A quick infographic on the importance of sun protection and the various results of sun damage
#wavelengths #causes ... #diagnosis #dermatology ... Acute effects of ... occupational disease evaluation ... Mechanisms and treatments
Acute Recurrent Pericarditis
= recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... Systemic symptoms: pulmonary ... manifestations, TREATMENT ... diagnosis #management #treatment ... #rheumatology #
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
syndromes current treatment ... risk of clonal evolution ... to acute myeloid ... cardiovascular or pulmonary ... #algorithm #hematology