15 results
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
pyelonephritis Most common cause ... uncharacterized fevers ... Consider BCx, CSF evaluation ... Diagnosis #Peds #EM ... SeriousBacterialIllness #Ddxof
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Diagnosis and Evaluation ... Identification of onset (acute ... symptoms (HA, nausea ... history #Diagnosis #EM ... Differential #Algorithm #Ddxof
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... At least 3 of (Acute ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... Presentation ​- Acute ... DIAGNOSIS: ​• Acute ... TREATMENT: ​• Acute
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation ... #summary #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... diagnosis #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... - ACS, AKI, acute ... organ damage • Treatment ... diagnosis #management #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... characterized by fever ... Causes: - Idiopathic ... , breast CA - Hematologic ... Treatment: - Systemic
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Fever >38.5 2. ... • SJS/TEN • Acute ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Acutely (hours ... starting amiodarone treatment ... toxicity (e.g., acute ... Fever 4. ... macrophages Treatment