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diagnosis management oncology leukemia syndrome algorithm cancer cardiology chronic cll comparison damage dermatology differentiation exposure hemophagocytic hlh leukostasis lymphocytic lymphohistiocytosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... : • Common: fever ... Imaging: CXR- pulmonary ... diagnosis #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... Headaches, bone pain, fever ... smear: Blasts APML ... #Leukemia #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... At least 3 of (Acute ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation ... #summary #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... - ACS, AKI, acute ... organ damage • Treatment ... diagnosis #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... microglobulin Treatment ... Transform to DLBCL, PML ... ’s lymphoma or acute ... workup #oncology #hematology
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... RED FLAGS: Fever ... Systemic symptoms: pulmonary ... manifestations, TREATMENT ... #rheumatology #
A quick infographic on the importance of sun protection and the various results of sun damage
#wavelengths #causes ... Toxicol Appl Pharmacol ... Acute effects of ... occupational disease evaluation ... Mechanisms and treatments
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... risk of clonal evolution ... to acute myeloid ... cardiovascular or pulmonary ... #algorithm #hematology
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