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diagnosis management comparison druginduced sle table algorithm bleeding bruising cancer cardiology differential dil erythematosus hemophagocytic hemostasis hlh lymphohistiocytosis mds myelodysplastic
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... Positive in 60-80% of cases ... life-threatening • Treatment ... management of SLE • Evolution ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... cutaneous-DIL • Evolution ... life-threatening • Treatment ... comparison #table #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management Summary ... old, ~10,000 new cases ... transformation to acute ... only curative treatment ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Drugs, Unknown cause ... Treatment: • ... inhibitors under evaluation ... diagnosis #management #treatment ... #summary #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... At least 3 of (Acute ... , and CXR with pulmonary ... Transfusion #Reactions #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... • Warfarin • Acute ... discern these causes ... Liver disease • Acute ... Differential #Diagnosis #Hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
constitutional symptoms • Treatment ... Discontinuation of causal ... cutaneous-DIL • Evolution ... #DIL #rheumatology ... #diagnosis #treatment
Acute Recurrent Pericarditis = recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
symptoms, >1/4 of AP cases ... Systemic symptoms: pulmonary ... manifestations, TREATMENT ... diagnosis #management #treatment ... #rheumatology #
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... risk of clonal evolution ... to acute myeloid ... cardiovascular or pulmonary ... #algorithm #hematology
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