10 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... gastric bypass), LFT ... (liver disease) ... - Bone marrow evaluation ... #hematology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
and Evaluation ... Identification of onset (acute ... symptoms (HA, nausea ... history (cardiac, liver ... Differential #Algorithm #Ddxof
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... headache, malaise) → Acute ... #Pregnancy #hepatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... At least 3 of (Acute ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... • Warfarin • Acute ... discern these causes ... disease • Acute ... #Hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... survival is 93-95% Pathophysiology ... symptoms are not caused ... heart (2-5%), liver ... (pain/abnormal LFT
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... protein C and S Pathophysiology ... DIC • Severe Liver ... #Coagulation #diagnosis ... #management #hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
Hospitalization - Pathophysiology ... during clinical evaluations ... blood loss or acute ... deficiencies • Renal, liver ... #pathophysiology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
first step in evaluation ... Sarcoidosis) • Liver ... inflammation (acute ... #differential #diagnosis ... #hematology