15 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Disease, MDS, Chemotherapy ... , Liver disease, ... liver disease, ... differential #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
can indicate disease ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Acute leukemias ... Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Management #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Syndromes #diagnosis #hematology ... #oncology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
for workup, including ... , deficiency anemia ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... Matthew Ho, MD
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... disease), HBsAg ... - Bone marrow evaluation ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... B-cell activation ... Hodgkin lymphoma and leukemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... leukemia • Solitary ... Sarcoidosis) • Liver ... anemia • Other