19 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and ... Cell Crises Clinical ... #Hematology #SickleCell ... Manifestations #Workup ... #Algorithm #Ddxof
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... : Chronic disease ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
of SLE versus DIL ... • Immunologic Workup ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... for workup, including ... : Acute blood loss ... Vasculitides, IBD, Celiac disease ... Glucocorticoids, IL
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.
Evaluation of Chronic ... Causes of acute ... Systemic disease ... leukocytes and occult blood ... #algorithm #workup
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... fulminans - DIC ... Autoimmune Vasculitis (lupus ... deficiency Work ... #Causes #dermatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... Discontinuation of causal ... • Evolution: ... #DIL #rheumatology ... diagnosis #treatment #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... ABO incompatible blood ... • Severe Liver Disease ... #treatment #management ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor and lupus ... • Warfarin • Acute ... discern these causes ... • Acute DIC • ... Differential #Diagnosis #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Fibrinogen level, ↑ sIL ... • Autoimmune diseases ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management