12 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Disease Acute ... Supportive with treatment ... of SCD crisis Acute ... hepatomegaly and anemia ... hepatology #hepatitis #differential
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
DiabetesB12 deficiency, Uremia ... • Inflammatory/AI ... Vasculitis, Sjogren's, Lupus ... , Acute intermittent ... Peripheral #Neuropathy #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hematology for workup ... Nonmalignant hematologic: Acute ... blood loss, Acute ... infections, TB, Acute ... Severe trauma, Acute
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Pleural effusions • Acute ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronicity: • Acute ... infections (bacterial), acute ... Send for cell count ... • Acute = Viral ... #differential #
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
: syßtemic lupus ... anemia, obstructive ... uropathy, post-acute ... Acute oliguric kidney ... #Hyperkalemia #Differential
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
presents with an acute ... • An evaluation ... for giant cell ... • Normocytic anemia ... normal and can help differentiate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... presentations and disease ... cardiac output - Acute ... peritonitis - Acute ... 30mmHg) - Severe anemia
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
phlebotomy/ blood work ... during clinical evaluations ... blood loss or acute ... of renal disease ... pathophysiology #differential