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diagnosis hematology management oncology algorithm differential rheumatology syndrome aplastic cancer chronic classification disorders erythematosus gap globulin hiv lymphomas lymphoproliferative mds
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... ALL (Acute Lymphoblastic ... Lymphadenopathy AML (Acute ... Blasts APML (Acute ... Leukemia (CLL)
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... leukemia #CLL ... #workup #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
common - T Cell ... ~10% - B-Cell ... Responsive to Treatment ... Treated Like Acute ... Leukemias, very
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Treatment: • Consider ... stem cell transplant ... progress to MDS or acute ... leukemia • Associated ... diagnosis #management #treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Allogeneic stem cell
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral ... Syndrome Acute ... presentation of acute ... of infection Acute ... Labs: • CD4+ T-cell
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Angioimmunoblastic T-cell ... Pleural effusions • Acute ... : • Chronic B-cell ... Hodgkin lymphoma and leukemia
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
presents with an acute ... • An evaluation ... for giant cell ... • Normocytic anemia ... TREATMENT: • The
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... myeloma • Plasma cell ... Viral infections (acute ... Thalassemia, Sickle cell ... inflammation (acute
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... to acute myeloid ... leukemia (AML). ... disease tolerate anemia ... with repeated red cell
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