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diagnosis differential hematology management oncology classification rheumatology syndrome algorithm diseases lung allergy arthritis cardiology dermatology elevation hepatology ild interstitial laboratory
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... ALL (Acute Lymphoblastic ... extramedullary disease ... Lymphadenopathy AML (Acute ... Blasts APML (Acute
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Manifestations of Sickle Cell ... Disease Acute ... sickle cell hepatic ... Supportive with treatment ... hepatomegaly and anemia
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm Look for surgical abdomen Upper quadrant: R/O cardiac,
Diffuse Acute Abdominal ... musculoskeletal causes ... Ketoacidosis) • Sickle cell ... anemia • Musculoskeletal ... syndrome #Diffuse #Acute
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... days - Examples: Acute ... reaction, Haemolytic disease ... glomerulonephritis, Systemic lupus ... classification #comparison
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Acute ... • Hemolytic anemia ... Splenomegaly, Sickle Cell ... End-stage renal disease
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Crisis Sickle-cell ... disease - an autosomal ... Sickle cell disease ... 2) Aplasia - Acute ... of the baseline anaemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... Myeloproliferative Disease ... factor (GCSF) treatments ... Workup: • Complete
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... Polymyositis-dermatomyositis, Lupus ... pneumonia (DIP), Acute ... Eosinophilic pneumonia: Acute ... Pulmonary Langerhans cell
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Differential Diagnosis Acute ... Traumatic Rupture, Acute ... Endocarditis, Acute ... Dysfunction, Post Acute ... Salmonella), Giant Cell
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