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hematology management rheumatology differential algorithm oncology sle arthritis causes cll erythematosus lymphocytic systemic thrombocytosis approach blastomycosis cancer ckd classification comparison
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
can indicate disease ... • Neutropenia, anemia ... ’s lymphoma or acute ... #Leukemia #diagnosis ... #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Acute leukemias ... Chronic leukemia ... extramedullary disease ... - infiltrates (anemia ... Hematology #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... chemotherapy for low-risk disease
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... Iron deficiency anemia
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... : Chronic disease ... Erythematosus #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myelogenous Leukemia ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... life-threatening • Treatment ... : Chronic disease ... #rheumatology #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell ... Hodgkin lymphoma and leukemia
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... ), RA, crystal disease ... spondyloarthropathies, lupus ... Send for cell count ... rheumatology #approach #workup
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