10 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Disease Acute ... sickle cell hepatic ... Supportive with treatment ... hepatomegaly and anemia ... hepatology #hepatitis #differential
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm
Look for surgical abdomen
Upper quadrant: R/O cardiac,
Diffuse Acute Abdominal ... Pain (<72 hours ... ) - Differential ... Ketoacidosis) • Sickle cell ... anemia • Musculoskeletal
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
- Differential ... (Ischemia) - Acute ... Occlusion • Sickle Cell ... Anemia • Peripheral ... Vascular Disease
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... permanent alopecia Differential ... Arthritis: • Joint pain ... lymphopenia, low PLT • Anemia ... : • Chronic B-cell
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... spondyloarthropathies, lupus ... Send for cell count ... rheumatology #approach #workup ... #differential #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Pain in LN ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Hodgkin Lymphoma Treatment
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
presents with an acute ... proximal muscle pain ... for giant cell ... • Normocytic anemia ... normal and can help differentiate
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... myeloma • Plasma cell ... anemia • Other ... Gap #ProteinGap #differential
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
syndromes current treatment ... algorithm 2018. ... to acute myeloid ... tolerate anemia ... with repeated red cell