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diagnosis hematology causes management algorithm rheumatology oncology arthritis classification laboratory lung neurology acute cardiology elevation hemolytic hiv ild infectiousdiseases interstitial
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Liver diseases ... - Sickle cell anemia ... - Renal diseases ... , Liver diseases
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Manifestations of Sickle Cell ... Disease Acute ... sickle cell hepatic ... Supportive with treatment ... #SickleCell #Disease
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
, CLL, lymphoma, ... cold agglutin disease ... Hemoglobinopathies (e.g. sickle cell ... disease, thalassemias ... Hypersplenism, Wilson's disease
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... disease (diverse ... Cold agglutinins disease ... , Hemoglobin H disease ... Diagnosis #Algorithm #workup
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... Connective Tissue Disease ... connective tissue disease ... Pulmonary Langerhans cell ... Interstitial #Lung #Diseases
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
RBC turnover • Acute ... • Hemolytic anemia ... Splenomegaly, Sickle Cell ... End-stage renal disease ... Diagnosis #DM2 #Differential
Diffuse Acute Abdominal Pain (<72 hours) - Differential Diagnostic Algorithm Look for surgical abdomen Upper quadrant: R/O cardiac,
Diffuse Acute Abdominal ... • Peptic ulcer disease ... • Metabolic disease ... Ketoacidosis) • Sickle cell ... anemia • Musculoskeletal
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... factor (GCSF) treatments ... Workup: • Complete ... blood count with differential
Causes of Severe Aortic Regurgitation - Differential Diagnosis Acute: • Leaflet: Traumatic Rupture, Acute Infective Endocarditis, Acute
Fever, Whipple Disease ... Arteritis, Crohn Disease ... Salmonella), Giant Cell ... Arthritis, IgG4 Disease ... , Cogan's Disease
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