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diagnosis oncology management algorithm differential leukemia mds myelodysplastic aplastic cancer chronic classification cll gap globulin hodgkins lymphocytic lymphoma myelodysplasia plasmacytoma
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Elevated Platelet ... for workup, including ... , deficiency anemia ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... marrow studies Treatment ... #diagnosis #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
bleeding from low platelets ... Treatment: • Consider ... stem cell transplant ... progress to MDS or acute ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... transformation to acute ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
basophilia, and thrombocytosis ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Hodgkin Lymphoma Workup ... - Low Hb and platelets ... Hodgkin Lymphoma Treatment ... classification #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... myeloma • Plasma cell ... changes (POEMS syndrome ... anemia • Other
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
to acute myeloid ... disease tolerate anemia ... with repeated red cell ... neutrophils or platelets ... #algorithm #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• No CRAB - no anemia ... Diagnostic Evaluation ... Bone marrow Treatment ... Oncology #Diagnosis #Workup ... #Hematology
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