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diagnosis differential hematology management sle erythematosus causes druginduced systemic workup activation algorithm anemia autoantibodies bleeding bruising classification comparison criteria disorders
Algorithm for the Evaluation of Thrombocytopenia #Diagnosis #Hematology #Thrombocytopenia #Workup #Algorithm #Ddxof
Algorithm for the Evaluation ... of Thrombocytopenia ... #Diagnosis #Hematology ... #Thrombocytopenia ... Workup #Algorithm #Ddxof
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... • Evolution: ... Workup: - ANA ... management of SLE • Evolution ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... of SLE versus DIL ... Workup: - ANA ... management of SLE • Evolution ... Management #Summary #rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
Criteria - Systemic Lupus ... ACUTE CUTANEOUS LUPUS ... (<1000/MM3) - THROMBOCYTOPENIA ... IMMUNOLOGIC CRITERIA - ANA ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Neurological 12% - Thrombocytopenia ... Auto-Antibodies: - ANA ... Diagnosis and Lupus ... #differential #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... function test, ANA ... - Bone marrow evaluation ... patients with thrombocytopenia ... Causes #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation (DIC ... microangiopathy: Thrombotic thrombocytopenic ... usually IgG) (e.g. lupus ... differential #diagnosis #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... : -10% of all lupus ... Workup: - ANA ... • Evolution: ... #DIL #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... leukopenia, anemia, and thrombocytopenia ... Diagnosis #Management #Hematology ... #Rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... administration, evaluation ... The appropriate evaluations ... Differential #Diagnosis #Hematology
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