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diagnosis treatment druginduced erythematosus summary syndrome activation cardiology cerebritis cns comparison constrictive echocardiogram hematology hemophagocytic hlh lymphohistiocytosis macrophage mas neurology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... versus DIL • ... of SLE • Evolution ... #lupus #Systemic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... , SCLE-DIL (terbinafine ... months to years) Systemic ... of SLE • Evolution ... #table #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... autoantibodies that will cause ... #rheumatology # ... cerebritis #diagnosis #management
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View Young Lupus patient admitted to hospital new onset HFpEF.
Pericarditis on POCUS ... What do you see ... Did have tap next ... #Pericarditis #CP ... #clinical #cardiology
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 Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lupus erythematosus ... lupus erythematosus ... [SLE], AOSD) • ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... , SCLE-DIL (terbinafine ... • Evolution: ... #DIL #rheumatology ... diagnosis #treatment #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Autoimmune diseases: SLE ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... • Nephrogenic DI ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
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