11 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... to 1:1 F:M • Clinical ... , SCLE-DIL (terbinafine ... months to years) Systemic ... of SLEEvolution
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... versus DIL • ... of SLEEvolution ... #lupus #Systemic
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... autoantibodies that will cause ... #SLE #CNS #neurology ... cerebritis #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lupus erythematosus ... Fever is the main clinical ... lupus erythematosus ... [SLE], AOSD) • ... Syndrome #Diagnosis #Management
Constrictive Pericarditis on POCUS Echocardiogram - Subcostal View

Young Lupus patient admitted to hospital new onset HFpEF.
Pericarditis on POCUS ... What do you see ... could pinpoint the cause ... Did have tap next ... Echocardiogram #clinical
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... , SCLE-DIL (terbinafine ... Discontinuation of causal ... • Evolution: ... diagnosis #treatment #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
Cardiac Arrest - Guidelines for Crises in Anaesthesia

The probable cause is one or more of: something
senior on-call / dial ... delegate task of evaluating ... Check breathing system ... • See Boxes B ... Checklist #Diagnosis #Management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
other, more common causes ... Change breathing system ... Plan admission to critical ... therapy later DIC ... Checklist #Diagnosis #Management
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... PMR) is a common systemic ... disease of unknown cause ... • An evaluation ... greater than 6 dL