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diagnosis rheumatology differential druginduced erythematosus guillain summary syndrome systemic arteritis cerebritis cns comparison dil erythema gbs gca giantcell gravis guillainbarre
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management ... 40, F:M 9:1 • Clinical ... Positive in 60-80% of cases ... life-threatening • Treatment ... of SLE • Evolution
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Usual therapeutic management ... of SLE • Evolution
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... autoantibodies that will cause ... #CNS #neurology ... cerebritis #diagnosis #management
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... renal histological evaluation ... #treatment #management ... #rheumatology #nephrology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... meningococcal, H1N1) Clinical ... Clinical Features ... Syndrome #diagnosis #management ... #treatment #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Approach (when evaluation ... 109 mm Hg) with clinical ... Coarctation of aorta ... Neurologic disorders ... , and Guillain-Barre
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Incidence: 1 to 2 cases ... transplantation CLINICAL ... and cauda equina TREATMENT ... Syndrome #diagnosis #management ... #neurology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Autoimmune diseases: SLE ... Treatment: • ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... myopathy, Guillain-Barré ... GBS), systemic lupus ... erythematosus (SLE ... myopathy #diagnosis #management
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Clinical Picture ... Clinical DX: - ... Gravis #diagnosis #management ... #neurology
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