20 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... of Sickle Cell Crises ... #Hematology #SickleCell ... #Complications ... #Algorithm #Ddxof
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... or workup for specific ... /µL Workup • Screen ... consider tissue biopsy ... Differential #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
can indicate disease ... kinase (BTK) Complications ... leukemia • GI complications ... Leukemia #diagnosis #workup ... #oncology #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... increased IgG4+ cells ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... , Schnitzler) Complications ... normal CK, normal biopsy ... #diagnosis #management ... #treatment #rheumatology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
hypocellular bone marrow biopsy ... Consider stem cell ... neutropenic fever) Complications ... Anemia #diagnosis #management ... #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... - Bone marrow evaluation ... BM aspiration/biopsy ... #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... • Immunologic Workup ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
thrombocytopenia Complications ... Transformation to large cell ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... hemeonc #diagnosis #management