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differential causes gastroenterology hematology algorithm iron nutrition abdominal b12 cobalamin diarrhea disorders gastrointestinal hepatic hepatology laboratory liverfailure management mds myelodysplasia
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
with anemia, diagnose ... inflammation or chronic ... tests Test for celiac ... disease with serology ... #Evaluation #workup
Chronic Diarrhea - Workup Osmotic: • Consider food diary and trial avoiding certain foods or meds, Consider
Chronic Diarrhea ... - Workup Osmotic ... certain foods or meds ... for celiac disease ... #testing #evaluation
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Elite athletes • Chronic ... Loss (without anaemia ... ): GI cancers, Donations ... Bleeding, Edema, Celiac ... #differential #diagnosis
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
- Differential Diagnosis ... have had prior evaluations ... , physical and testing ... bowel syndrome • Celiac ... ischemia • GI
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... Acute hemolysis, deficiency ... anemia, Rebound ... disease, Kawasaki ... • Infections: Chronic
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
liver disease, ... thrombopoietin deficiency ... can indicate a GI ... Hepatology #Laboratory #Diagnosis ... #Testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... smear, HIV/HCV testing ... . pylori test (GI ... changes), high MCV anemia ... - Bone marrow evaluation
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... skin pallor • GI ... related to IBD, celiac ... disease, other ... total body stores Evaluation
Celiac Disease - Diagnosis Algorithm IgA TTG has high sensitivity and specificity of ~ 98% and is
Celiac Disease - ... serologic marker for evaluating ... IgA deficiency affects ... pts need further testing ... #Disease #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myeloproliferative Disease ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis
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