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differential algorithm causes deficiency oncology gastroenterology leukemia management nutrition rheumatology thrombocytosis workup calculation cholangitis cll erythematosus euvolemic gastrointestinal hepatology hypervolemic
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Elite athletes • Chronic ... Loss (without anaemia ... Bleeding, Edema, Celiac ... Disease (IBD, cancer ... #differential #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... disorders • Celiac ... disease Tissue ... malignancy • Iron ... deficiency anemia
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... with anemia, diagnose ... inflammation or chronic ... tests Test for celiac ... disease with serology
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Drugs, H pylori, Celiac ... : Gl lesions / cancer ... disease (↑ hepcidin ... #differential #diagnosis ... #anemia #nutrition
Differential Diagnosis and Evaluation of Hyponatremia: 1) Identification of onset (acute vs. chronic) 2) Presence of symptoms (HA,
and Evaluation ... onset (acute vs. chronic ... 2) Presence of symptoms ... , liver, renal disease ... #EM #IM #Nephro
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac ... disease, Kawasaki ... • Infections: Chronic
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Iron ... kidney disease, ... infiltration (e.g. cancer ... Production #Index #hematology ... #diagnosis #calculation
Celiac Disease - Clinical Manifestations Gastrointestinal Manifestations: • Diarrhea, Loose stools, Dyspepsia, Flatulence, Chronic abdominal pain,
Celiac Disease - ... , Hepatitis • Iron-deficiency ... anaemia • Arthralgia ... #Disease #signs ... #symptoms #diagnosis
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
PSC) PSC is a chronic ... asymptomatic at diagnosis ... Care focuses on symptom ... clinical trial evaluation ... #Cholangitis #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
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