13 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... • B12/Folate ... Deficiency • Aplastic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential Diagnosis ... Spherocytosis, G6PD, PK, HbC ... , B12 deficiency ... #Differential #Diagnosis ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... disorders • Celiac ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Neutrophils - Low RBC ... • Dietary Deficiency ... and Folate Deficiency ... #Differential #Diagnosis
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
: Pyridoxine deficiency ... : Vitamin B12 or ... Folate deficiency ... #differential #diagnosis ... #hematology #microscopy
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Algorithm for the evaluation ... (RBC = red blood ... deficiency is present ... deficiency. ... #Diagnosis #Macrocytosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... bartonella (oroya fever ... #Differential #Diagnosis ... Algorithm #workup #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... article/S0002-9343(12 ... tachycardia or fever ... count on initial evaluation ... #CBC #hematology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... related to IBD, celiac ... total body stores Evaluation ... • Labs: - CBC ... #Cobalamin #Deficiency
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
deficiencies: Iron deficiency ... loss), Vitamin B12 ... , G6PD deficiency ... Production #Index #hematology ... #diagnosis #calculation