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differential algorithm anemia thrombocytosis aplastic bleeding causes cbc disorders ferritin hemolytic history iron management neutrophil nonpalpable oncology palpable pathophysiology pediatrics
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... disorders • Celiac ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... Algorithm #Causes #Hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... - Structural: Celiac ... #Diagnosis #Algorithm ... #ferritin #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Acute hemolysis, deficiency ... anemia, Rebound ... Vasculitides, IBD, Celiac ... #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... bartonella (oroya fever ... #Differential #Diagnosis ... Algorithm #workup #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... necrosis) • VIT K deficiency ... mountain spotted fever ... #hematology #rheumatology ... #nonpalpable #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology ... #diagnosis #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... tachycardia or fever ... count on initial evaluation ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Clinical Features in Evaluating ... or factor XIII deficiency ... Disorders #History #peds ... #pediatrics #diagnosis ... #hematology #primarycare
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