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hematology differential algorithm management workup causes gastroenterology hemolytic iron rheumatology thrombocytosis agglutinin b12 carcinoma cbc cobalamin cold disorders falls ferritin
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Anemia In patients ... with anemia, diagnose ... tests Test for celiac ... disease with serology ... #Anemia #Gastrointestinal
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... bartonella (oroya fever ... ARUPLabs #Hemolytic #Anemia ... #testing
Celiac Disease Testing Algorithm INDICATIONS FOR TESTING: Nonspecific symptoms (iron-deficiency anemia, failure to thrive, fever, skin
Celiac Disease Testing ... symptoms (iron-deficiency ... anemia, failure ... to thrive, fever ... #Disease #Testing
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... - Structural: Celiac ... disease, Tropical ... #Anemia #Differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... disorders • Celiac ... disease Tissue ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Acute hemolysis, deficiency ... anemia, Rebound ... Vasculitides, IBD, Celiac ... disease, Kawasaki
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... • Autoimmune diseases ... Degree of bandemia ... tachycardia or fever ... count on initial evaluation
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Symptoms: High fevers ... #hemolytic #anemia ... #hematology #diagnosis
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
autoantibodies (pernicious anemia ... Worsening macrocytic anemia ... wt loss • If anemia ... disease, other ... - CBC, PBS - anemia
Evaluation of suspected incomplete Kawasaki Disease 1. AHA consensus recommendations 2. Infants ≤6 months old on day ≥7
Evaluation of suspected ... old on day ≥7 of fever ... should undergo lab testing ... Albumin ≤3.0 g/dL, anemia ... #Diagnosis #Peds
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