26 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... hemolysis, deficiency anemia ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac ... disease, Kawasaki
Algorithm for the Evaluation of Kawasaki and Incomplete Kawasaki Disease:
Diagnosis
* Fever >5d
* Criteria (4/5)
  -
Algorithm for the Evaluation ... : Diagnosis * ... Fever >5d * Criteria ... #Peds #Pediatrics ... Workup #Algorithm #Ddxof
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... tachycardia or fever ... likelihood of negative clinical ... count on initial evaluation
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Carcinoma (RCC) - Diagnosis ... Management Summary Clinical ... Anemia (common) ... night sweats, fever ... with contrast Evaluation
Evaluation of suspected incomplete Kawasaki Disease

1. AHA consensus recommendations
2. Infants ≤6 months old on day ≥7
Evaluation of suspected ... incomplete Kawasaki Disease ... old on day ≥7 of fever ... if they have no clinical ... #Diagnosis #Peds
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... Lymphoma or other cancers ... gastric and breast cancer ... autoimmune hemolytic anemia
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Rapid onset of fever ... chronic liver disease ... immunosuppressive meds ... rash #cellulitis #dermatology ... #legs #clinical
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... B-LNH), solid cancers ... inhibitors under evaluation
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Clinical ... : • 80% have fever ... Leukocytosis, anemia ... Intervention: - Fevers ... foreign body, cancer
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... Differential Diagnosis ... Symptoms: High fevers ... #hematology #diagnosis