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diagnosis anemia hematology algorithm classification cobalamin management neurology abdominal approach extremity falls fat gastroenterology geriatrics leg low lower malabsorption morphologic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... (>100 fL) • B12 ... Classification #Differential
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
kidney disease, ... Megaloblastic: Vitamin B12 ... Alcohol use, Liver disease ... #differential # ... diagnosis #causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
RBCs on Smear • Chronic ... Reticulocytes, MCV ... • B12/Folate ... Disease • Marrow ... Diagnosis #Algorithm #Causes
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... , coeliac disease ... low #cobalamin #differential
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... have had prior evaluations ... poisoning • Celiac ... #Chronic #Causes ... #Differential #
Causes of Fat Malabsorption - Differential Diagnosis Biliary Duct Obstruction • Autoimmune— PBC, PSC • Infection— liver
- Differential ... liver fluke, HIV, CMV ... , celiac disease ... - Acquired • Chronic ... Pancreatic lipase deficiency
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... Legg-Calve-Perthes disease ... Neuropathy (DM, Vit B12 ... , B6, Cu deficiency ... #differential #
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... related to IBD, celiac ... disease, other ... total body stores Evaluation
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
or without back pain ... Check Vitamin B12 ... • Infectious causes ... • Nutritional Deficiency ... management #neurology #differential
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
Evaluation of Recurrent ... e.g., diabetic, B12 ... deficiency) ... : Joint pain, limited ... Falls #Diagnosis #Differential
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