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diagnosis differential algorithm cobalamin macrocytic classification hepatology low macrocytosis mcv thrombocytosis vitamin vitaminb12 aafp alkaline alp approach cirrhosis disorders elevatedmcv
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... Intestine: SIBO, Celiac ... disease, IBD, Lymphoma ... Stomach: Pernicious anemia
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron deficiency ... chronic kidney disease ... - Vitamin B12 ... Underproduction #Algorithm #hematology ... #differential #workup
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
• 812, Folate ... Deficiency • ... Hypothyroid • Liver Disease ... diagnosis #algorithm #hematology ... #workup
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... (>100 fL) • B12 ... Deficiency • ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac ... disease Tissue ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... of Iron Deficiency ... tests Test for celiac ... disease with serology ... #Evaluation #workup
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the evaluation ... the most likely cause ... recovery also causes ... of the initial work-up ... deficiency.
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... and Folate Deficiency ... • Liver Disease ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
chronic kidney disease ... Megaloblastic: Vitamin B12 ... Alcohol use, Liver disease ... differential #diagnosis #causes ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
• B12/Folate ... Deficiency • Aplastic ... of Chronic Disease ... Diagnosis #Algorithm #Causes ... #Hematology
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