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diagnosis differential algorithm cobalamin hepatology mcv alkaline alp cirrhosis classification elevatedmcv falls geriatrics hyophosphatasia macrocytic macrocytosis management mds morphologic myelodysplasia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm Low ... (>100 fL) • B12 ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... • Dietary Deficiency ... - Low Serum B12 ... and Folate Deficiency ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Approach - MCV) Low ... chronic kidney disease ... Megaloblastic: Vitamin B12 ... differential #diagnosis #causes ... #hematology
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... Autoimmune - Pernicious anaemia ... , coeliac disease
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... related to IBD, celiac ... disease, other ... total body stores Evaluation
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... Diagnosis Framework LOW ... PRODUCTION • Vitamin B12 ... Peptic ulcer disease ... , DIC-low factor
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Malnutrition • Wilson's disease ... • Pernicious anemia ... /B12 deficiency ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... hallmark for the disease ... result in severe anemia ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Workup: • Complete ... Syndromes #diagnosis #hematology
Evaluation of Recurrent Falls Core Concept: Maintaining an upright posture requires the integrated function of multiple systems. Disruption in
Evaluation of Recurrent ... embolism - Severe anemia ... e.g., diabetic, B12 ... deficiency) ... muscle wasting, slow
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