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diagnosis differential algorithm classification macrocytic cobalamin disorders elevatedmcv macrocytosis management mds morphologic myelodysplasia myelodysplastic nutrition oncology platelet platelets syndromes thrombocytopenia
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... chronic kidney disease ... Megaloblastic: Vitamin B12 ... differential #diagnosis #causes ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach ... • B12/Folate ... of Chronic Disease ... Diagnosis #Algorithm #Causes ... #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... inflammation) • Iron deficiency ... , B12 deficiency ... Non-megaloblastic: Liver disease ... Differential #Diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Corpuscular Volume (MCV ... (>100 fL) • B12 ... #MCV #Classification ... #Hematology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Approach to Hypoproliferative ... Deficiency • ... Hypothyroid • Liver Disease ... diagnosis #algorithm #hematology ... #workup
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Corpuscular Volume (MCV ... • Dietary Deficiency ... and Folate Deficiency ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV ... anemia (vegan, ... - Bone marrow evaluation ... #Workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... for workup, including ... Acute hemolysis, deficiency ... anemia, Rebound ... disease, Kawasaki
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
) Deficiency Etiology ... • Common Causes ... related to IBD, celiac ... disease, other ... total body stores Evaluation
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Nutritional: vitamin B12 ... Workup: • Complete ... Syndromes #diagnosis #hematology
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