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diagnosis cobalamin hematology nutrition cirrhosis decrease dm2 elevation false hba1c hepatology hgba1c increase laboratory low management mcv mds morphologic myelodysplasia
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... Intestine: SIBO, Celiac ... disease, IBD, Lymphoma ... #B12 #Deficiency
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Drugs, H pylori, Celiac ... #Deficiency #Causes ... #differential # ... diagnosis #anemia
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... Megaloblastic: Vitamin ... B12 deficiency, ... morphologic #mcv #differential ... #diagnosis #causes
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... , coeliac disease ... low #cobalamin #differential
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... RBC turnover • Iron ... deficiency • ... • Hemolytic anemia ... End-stage renal disease
Causes of Anemia in Cirrhosis - Differential Diagnosis Framework LOW RETIC INDEX - ↓ PRODUCTION • Vitamin
Causes of Anemia ... in Cirrhosis - Differential ... PRODUCTION • Vitamin ... B12 deficiency, ... Alcohol related, Iron
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... • Common Causes ... related to IBD, celiac ... disease, other ... , can consider IM
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... • Nutritional: vitamin ... B12 or folic acid ... rings of excess iron ... blood count with differential
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